On offense, it is hard to imagine JT or Burden being unseated at their respective positions. I guess they are as close to a "lock" as we have. In the next tier down from that in the "likely to start" category we have Bryan (I like him at OT) and Jeune at WR. Devine is in control of his own destiny the way I see it, but I have no idea how that will end up. He will be in a huge battle with Morgan, Griffin, Klock and the like in the next tier below that, which I will call "highly competitive".
In the "I have no idea" category we have ABs, BBs, and remaining WR. It is highly likely the ABs who played the most last year will be pushed down the depth chart. BB is a toss up. Maybe MM holds an edge, albeit razor thin. I can't pretend to know how WR battles are going.
On defense, things are even less settled in my mind. Along the line, I would say Gamble will have a major role, hopefully at SDE on run-likely downs. Freeman will have a major role, but he will be pushed more than ever before. If I had to guess, I would say Kallon will remain on the second string with somebody like Branch pushing him to the bench. In the back 7 Davis and Gray are in the likely to start category. The rest is a crapshoot.