Well … it could. But I'm betting that it won't.
Most shotgun spread offenses in college are basically double options with some passing. Same as what we used to run, except that there's no initial BB/B gap read. (Mind, the plays can be to the B gap too.) The QB reads the DE (usually) then either keeps or hands off/pitches or (RPO) throws off of play action. The RB goes to the designated hole - if DE bites - or blocks if he doesn't. You are thinking that we'll be running a true pro style and, if we do, then there will be two blocks (usually) to read both at about the same place. But, again, I doubt we'll do that; it would waste the running ability of our QBs and slow down the game, to our disadvantage.
Also, since Benson ran out of a shotgun spread (the real high school offense) in high school, I doubt he'll have much problem adjusting. Provided, that is, that can return to health in time for the spring. But we'll see.