First, after two games in a row against top teams, with a lot of emotion, I can see us have a let down and stumble in this game. I can also see Narduzzi put together a great game plan and have his players gigged up after being "dissed" at the end of last year's game. I can see Pitt win outright--they're favored, and games are also about matchups and maybe they match up well against us. Both coaches and teams can take offense at last year's game, so either or both teams can come in motivated.
I don't think stacking the box is going to happen. UNC could have put in a goalline package throughout the second half (the ultimate in box-stacking). It's not that simple. I'm sure Carter would like a nice bubble screen and one man to beat.
Also, when Sims made his 50ish yard TD run, there were players in the secondary with an angle, and he turned on the jets and left them behind. Gibbs and Sims and some of our receivers can do that too. Pitt might put a spy on Sims, but that takes one player out of the pass rush or puts them in weak pass coverage. When you spy a player faster than you, you better have great angles or you just look silly.
I see a decent amount of Pitt blitzing, and attacking our guards, and shifts and overloads and other ways to confuse our line. That's our weak point, and that's what I'd attack.
That's also a reason to keep a TE or H-back available--we need another blocker or half-blocker. I'd look for Patenaude to have some fun with formations, and maybe play with tempo--not all fast, but where we set the pace fast or slow, depending on what we want.
I'm not sure what Narduzzi's going to do on offense--we looked pretty solid in the last two games, and I'd think we're going to look for more ways to bring mayhem.