'Cuse will likely sit Jerami Grant and not risk re-aggravating his back. At most he'll play limited minutes but they probably won't risk it after his ineffectiveness the last several games. This is good news for GT as that's one first round pick out of the game.
GT on offense:
Since GT has shown minimal ability to create for each other on offense and 'Cuse has the athletic advantage at near every position the open looks will be minimal, unless 'Cuse intends to leave guys open. GT guards will need to ball screen the 'Cuse guards to get in the lane AND someone will need to become a playmaker at the elbows.
GT on defense:
On defense Daniel Miller will need to play the game of his life on help-side D. I expect 'Cuse to view this as a game to get back on track and take advantage of their size, athleticism, and speed, which generally means more explosive plays at the rim.
GT coaching:
For anyone who wants to gauge GT scouting/coaching... let's see how many open looks Cooney gets. If he's not face-guarded and allowed to get off uncontested 3's then that is a clear sign that something critical is missing in coaching or not clicking with the players. The teams that have beaten 'Cuse have at minimum sold out to keep him from getting into a rhythm from behind the arc. Cooney is probably more athletic than almost all GT guards but not to the degree where switching off screens or forcing him to put the ball on the floor is unreasonable.