I am not sure how to take this. If I am the manager and we are playing a team full of mostly right handed pull hitters, I am not gonna put a weak outfielder in left. I would speculate that the manager will configure his outfield to provide the best match up against a particular opponent. Of course, if you only play three outfielders during the season, then you just have to make a decision about where each of those three can best help the team. For the Atlanta Braves, the data suggests the Acuna is the worst outfielder (doesn't judge balls well and gets late jumps), but has a excellent speed and a terrific arm - he plays right. I don't know; I personally
If you're a smart manager, you would. You have to be careful with the term "weaker." Most of these guys are not that far apart.
It has to do with how the ball comes off the bat. Left-fielders get a truer ball flight from a right-handed batter. A RF gets a slice from a RH batter. Most batters are right-handed. In addition, the longest individual throw for an outfielder (all throws home tend to be the same or similar length) is from RF to 3rd base. LF never throws to 1st. IN GENERAL (there are exceptions to every rule), your right fielder has the strongest arm in the outfield.
This started as a discussion about college outfielders, so to use professionals as examples is a little of a reach, although I used a PRO example with Bobby Bonilla in my original comment. There are times when you might face a team with more lefties or there may be a weird field, but those are uncommon occurrences that prove the rule rather than disproves it.
To your example of Acuna, Dale Murphy was a gold glove center fielder in the early 80's (originally came into the organization as a catcher). When the Braves brought Brett Butler up from the minors, they moved Dale to RF and put BB in center. This was because Dale was an outstanding outfielder with a strong arm. At the time, they played in Atlanta-Fulton County Stadium, which was a uniformly symetric field.